Interest in paromomycin for the treatment of visceral leishmaniasis (kala-azar)

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Interest in paromomycin for the treatment of visceral leishmaniasis (kala-azar)

Leishmaniasis is an important vector-borne disease, and it is classified as one of the most important tropical fly-borne infections. This disease can cause two types of clinical manifestations: cutaneous forms and visceral forms. Visceral leishmaniasis, which is also called kala-azar, is a very serious infection that can be fatal. The management of visceral leishmaniasis requires informed diagn...

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Visceral leishmaniasis (kala azar) in Karachi.

Visceral leishmaniasis (VL) or Kala-azar (KA) is a communicable disease caused by Leishmania donovani named after the discoverers, Leishman and Donovan both of whom reported on the organism simulataneously, Leishman from London in May, 1903 and Donovan in July, 1903. Except for Australia, it is endemic in many places in China, Africa, Southern Europe, South America, Russia and India where it is...

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Deaths in visceral leishmaniasis (Kala-azar) during treatment.

Twenty-seven out of five hundred and fifty three patients hospitalized for visceral leishmaniasis (Kala-azar) died during treatment with sodium antimony gluconate. Data from these patients were evaluated to find out the cause of death. Eight patients had associated diseases such as pulmonary tuberculosis (3), severe malnutrition (1), acute gastroenteritis (1), spleenic infarction (1), acute ren...

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Hormonal disturbances in visceral leishmaniasis (kala-azar).

This study presents a cross-sectional analysis of the hormonal alterations of patients with visceral leishmaniasis. The diagnosis was established by the bone marrow aspiration and polymerase chain reaction test. Primary adrenal insufficiency was observed in 45.8% of patients; low aldosterone/renin plasma ratio in 69.4%; low daily urinary aldosterone excretion in 61.1%; and low transtubular pota...

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Kala-azar (visceral Leishmaniasis) from Khotang.

Kala-azar is a chronic infection of reticuloendothelial system caused by flagellated protozoan, leishmania donovani injected into human host by the bite of the sand fly (phlebotomous) previously infected by biting and sucking the blood of a patient of leishmaniasis. It is characterized by irregular fever of long duration, large spleen and liver, anaemia, leucopenia and progressive emaciation. T...

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ژورنال

عنوان ژورنال: Therapeutics and Clinical Risk Management

سال: 2012

ISSN: 1178-203X

DOI: 10.2147/tcrm.s30139